Neural Control and Coordination

Learning Outcomes

  1. Understand the basic structure and function of the neural system.
  2. Explore the human neural system’s major components and divisions.
  3. Study the structure and function of a neuron and mechanisms of nerve impulse transmission.
  4. Comprehend reflex actions and how the central neural system coordinates these responses.
  5. Learn about sensory reception and processing, including the role of the eye and ear in perceiving stimuli.

The human body maintains homeostasis through the coordination of various organs and organ systems. This coordination ensures that different organs interact and complement each other in a synchronized manner. For instance, during physical exercise, increased energy demand leads to higher oxygen needs, which in turn results in an increase in respiration rate, heart rate, and blood flow. Once physical activity ceases, these processes gradually return to their normal state. The neural system and endocrine system work together to integrate and coordinate all activities, ensuring the organs function in harmony. The neural system provides a rapid and organized response network through point-to-point connections, while the endocrine system controls chemical integration via hormones.

Neural System

The neural system across the animal kingdom varies in complexity. In lower organisms like Hydra, the neural system is a simple network of neurons. Insects exhibit more organization with a brain, ganglia, and other neural structures. Vertebrates possess a highly developed neural system with more complex functions.

Human Neural System

The human neural system is divided into two major parts:

  1. Central Neural System (CNS): Comprises the brain and spinal cord, acting as the site for information processing and control.
  2. Peripheral Neural System (PNS): Includes all nerves associated with the CNS. The nerve fibers of the PNS are divided into two types:
  • Afferent fibers: Transmit impulses from tissues or organs to the CNS.
  • Efferent fibers: Transmit regulatory impulses from the CNS to target tissues or organs.

The PNS is further classified into two divisions:

  1. Somatic Neural System: Relays impulses from the CNS to skeletal muscles.
  2. Autonomic Neural System: Transmits impulses from the CNS to involuntary organs and smooth muscles. It is divided into the sympathetic and parasympathetic neural systems. The visceral nervous system is a part of the PNS that connects the CNS with the internal organs (viscera), ensuring bidirectional communication.

Neuron as Structural and Functional Unit

A neuron is the structural and functional unit of the neural system. Neurons consist of three primary components:

  1. Cell body: Contains cytoplasm, organelles, and Nissl’s granules.
  2. Dendrites: Short, branched fibers that carry impulses towards the cell body and contain Nissl’s granules.
  3. Axon: A long fiber that carries impulses away from the cell body, terminating in synaptic knobs that house neurotransmitters. Neurons can be:
  • Multipolar (one axon, multiple dendrites, found in the cerebral cortex).
  • Bipolar (one axon, one dendrite, present in the retina).
  • Unipolar (one axon, typically found during the embryonic stage).

Axons are either myelinated or unmyelinated. Myelinated fibers are surrounded by Schwann cells, which form a myelin sheath. The gaps between myelin sheaths are called nodes of Ranvier. Unmyelinated fibers are enclosed by a Schwann cell but lack a myelin sheath. Myelinated fibers are present in spinal and cranial nerves, while unmyelinated fibers are common in the autonomic and somatic neural systems.

Important Note:

Myelination speeds up the transmission of nerve impulses, while unmyelinated fibers transmit impulses more slowly.

Generation and Conduction of Nerve Impulse

Neurons are excitable cells due to their polarized membrane state. The resting membrane has more K+ inside the axoplasm and more Na+ outside. This creates an ionic gradient, which is maintained by the sodium-potassium pump. When a stimulus is applied, the membrane becomes permeable to Na+, allowing an influx of sodium ions and reversing the polarity at that site. This is called depolarization, and the resulting potential difference is termed the action potential or nerve impulse. The action potential travels along the axon through the following mechanism:

  1. At the site of stimulus (point A), Na+ enters the membrane, reversing the polarity.
  2. A current flows along the inner surface of the membrane from point A to point B.
  3. The outer surface current flows from point B to point A, completing the circuit.
  4. This process repeats along the axon, transmitting the impulse.

After depolarization, K+ diffuses out of the membrane to restore the resting potential.

Transmission of Impulses

Synapses are junctions where nerve impulses transfer between neurons. There are two types of synapses:

  1. Electrical Synapses: The membranes of pre- and post-synaptic neurons are close enough for electrical current to pass directly, ensuring rapid transmission.
  2. Chemical Synapses: The pre- and post-synaptic neurons are separated by a synaptic cleft, where neurotransmitters facilitate impulse transmission.

At a chemical synapse, neurotransmitters are released into the synaptic cleft, bind to specific receptors on the post-synaptic membrane, and trigger the opening of ion channels. This may generate either an excitatory or inhibitory potential in the post-synaptic neuron.

Central Neural System

The CNS controls all voluntary and involuntary actions, integrating complex sensory, motor, and cognitive functions.

Forebrain

The forebrain comprises the cerebrum, thalamus, and hypothalamus. The cerebrum is divided into left and right hemispheres connected by the corpus callosum. The outer layer, the cerebral cortex, contains motor, sensory, and association areas. Below the cerebrum is the thalamus, a coordination center for sensory and motor signals. The hypothalamus below the thalamus controls body temperature, hunger, thirst, and hormonal secretions.

Important Note:

The limbic system, including the amygdala and hippocampus, alongside the hypothalamus, regulates emotions, motivation, and sexual behavior.

Midbrain

The midbrain lies between the forebrain and hindbrain, consisting of corpora quadrigemina, which processes visual and auditory inputs.

Hindbrain

The hindbrain includes the pons, cerebellum, and medulla oblongata. The pons connects various brain regions, the cerebellum helps maintain balance, and the medulla regulates respiration, heart rate, and gastric secretions.

Reflex Action and Reflex Arc

A reflex action is an automatic, involuntary response to a stimulus, typically involving the spinal cord and not requiring conscious thought. The reflex arc consists of an afferent neuron that carries the stimulus to the CNS and an efferent neuron that transmits the response to the target organ.

Sensory Reception and Processing

Sensory organs detect environmental changes and send signals to the CNS for processing. The CNS then interprets these signals and coordinates appropriate responses.

Eye

The human eye is a complex organ responsible for vision. It is a nearly spherical structure with three layers:

  1. Sclera: The outer layer, which is dense and protective.
  2. Choroid: The middle layer, rich in blood vessels.
  3. Retina: The innermost layer containing photoreceptor cells.

There are two types of photoreceptor cells:

  • Rods: Responsible for twilight (scotopic) vision.
  • Cones: Responsible for daylight (photopic) vision and color perception.

Mechanism of Vision

Light entering the eye through the cornea and lens is focused on the retina, generating impulses in the rods and cones. The photopigments, composed of opsin and retinal, undergo structural changes, leading to the generation of action potentials. These impulses travel to the visual cortex of the brain, where the image is processed and recognized.

Ear

The ear functions in hearing and balance and is divided into three sections:

  1. Outer ear: Consists of the pinna and auditory canal.
  2. Middle ear: Contains the tympanic membrane and ossicles (malleus, incus, st

apes).

  1. Inner ear: Includes the cochlea and vestibular apparatus.

Mechanism of Hearing

Sound waves collected by the pinna cause the tympanic membrane to vibrate. These vibrations pass through the ossicles to the oval window of the cochlea, where they generate waves in the inner ear fluids. The basilar membrane movements bend the hair cells, generating nerve impulses sent to the auditory cortex for sound interpretation.

Comparative Table

AspectRodsCones
FunctionTwilight (scotopic) visionDaylight (photopic) vision and color
SensitivityHigh sensitivity in dim lightLow sensitivity in bright light
PigmentRhodopsin (visual purple)Three pigments (for red, green, and blue)

Key Concept

The vestibular apparatus in the inner ear, consisting of semi-circular canals and the otolith organ, maintains balance by detecting changes in body position and motion.

MCQ

Which part of the ear is responsible for determining the pitch of a sound?
Answer: Cochlea.

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